SCHEMBL7571402

SCHEMBL7571402

C=C(C)C(=O)O[Si](C(C)CC)(C(C)CC)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
ALDH1A1 P00352 1/20 0.34
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7575125 0.93 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL7571667 0.86 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL5699078 0.86 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL5699026 0.86 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL7567653 0.84 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL5699047 0.83 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL7571415 0.83 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL2185447 0.81 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL7568455 0.77 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL2184912 0.77 TSHR (0.45) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6498264-B2 REACTING A CHLOROSILANE COMPOUND WITH ACRYLIC OR METHACRYLIC ACID IN THE PRESENCE OF A BASIC COMPOUND; PROTECTIVE HYDROLYSABLE COATINGS FOR SHIP BOTTOMS; NONTOXIC; POLLUTION CONTROL; KINETICS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-12-24 US disclosed
US-20020128503-A1 Silyl (meth)acrylates having bulky substituent group and preparation thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-09-12 US disclosed
EP-1238980-A1 Silyl (meth)acrylates having bulky substituent group and preparation thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-09-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128503-A1 Silyl (meth)acrylates having bulky substituent group and preparation thereof SMS, MASTL, ACR TSHR 4007/4885ALDH1A1 791/4885THRB 1319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.