Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 4/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.76 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | IDO1 | P14902 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | HTR2C | P28335 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetylserotonin SCHEMBL422165 | 0.86 | SPR (1.00) | SPRKDM4ECYP2D6ALDH1A1NPSR1 | |
| Acetylserotonin SCHEMBL30295379 | 0.86 | SPR (1.00) | SPRKDM4ECYP2D6ALDH1A1NPSR1 | |
| Acetylserotonin SCHEMBL29375184 | 0.86 | SPR (1.00) | SPRKDM4ECYP2D6ALDH1A1NPSR1 | |
| Acetylserotonin SCHEMBL29669245 | 0.85 | SPR (0.97) | SPRKDM4ECYP2D6ALDH1A1NPSR1 | |
| Acetylserotonin SCHEMBL31488730 | 0.85 | SPR (0.97) | SPRKDM4ECYP2D6ALDH1A1NPSR1 | |
| Acetylserotonin SCHEMBL7569197 | 0.83 | SPR (0.83) | SPRKDM4ECYP2D6ALDH1A1NPSR1 | |
| SCHEMBL1127784 | 0.80 | HTR2C (1.00) | SPRKDM4ECYP2D6ALDH1A1NPSR1 | |
| SCHEMBL29471374 | 0.80 | HTR2C (1.00) | SPRKDM4ECYP2D6ALDH1A1NPSR1 | |
| Acetylserotonin SCHEMBL28474145 | 0.80 | SPR (0.86) | SPRKDM4ECYP2D6ALDH1A1NPSR1 | |
| Acetylserotonin SCHEMBL28475510 | 0.80 | SPR (0.86) | SPRKDM4ECYP2D6ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083144-A1 | METHOD OF TREATMENT USING DEUTERIUM COMPOUNDS | BELL RUPERT CHARLES (US) | 2002-10-24 | — | — | WO | disclosed |
| US-6376531-B1 | ANTIDEPRESSANTS | BELL RUPERT CHARLES (US) | 2002-04-23 | — | — | US | disclosed |