Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991491 | 0.90 | KCNH2 (0.48) | KCNH2SLC2A1CNR1CNR2CYP2C9 | |
| SCHEMBL28919607 | 0.84 | KCNH2 (0.48) | KCNH2SLC2A1CNR1CNR2CYP2C9 | |
| SCHEMBL7595465 | 0.83 | ALOX5 (0.54) | KCNH2SLC2A1CYP2C9GAATDP1 | |
| SCHEMBL38650914 | 0.82 | KCNH2 (0.47) | KCNH2SLC2A1CNR1CNR2CYP2C9 | |
| SCHEMBL12301187 | 0.82 | SLC2A1 (0.47) | KCNH2SLC2A1CNR1CNR2CYP2C9 | |
| SCHEMBL11196561 | 0.82 | HTR1B (0.56) | KCNH2SLC2A1CYP2C9GAATDP1 | |
| SCHEMBL4885527 | 0.81 | IDO1 (0.54) | KCNH2CYP2C9GAATDP1L3MBTL1 | |
| SCHEMBL17912887 | 0.81 | GAA (0.56) | KCNH2SLC2A1CNR1CNR2CYP2C9 | |
| SCHEMBL9485052 | 0.81 | SLC2A1 (0.49) | KCNH2SLC2A1CNR1CNR2CYP2C9 | |
| SCHEMBL28920259 | 0.81 | GAA (0.56) | KCNH2SLC2A1CNR1CNR2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1157961-A | — | — | None | — | — | JP | disclosed |
| EP-0713486-B1 | PHOTOCHROMIC NAPHTHO(2,1-B)PYRANS | PILKINGTON PLC (GB) | 2002-07-17 | — | — | EP | disclosed |
| EP-0713486-A1 | PHOTOCHROMIC NAPHTHO(2,1-B)PYRANS | PILKINGTON PLC (GB) | 1996-05-29 | — | — | EP | disclosed |
| US-5520853-A | LIGHT SENSITIVE COMPOUNDS FOR POLYMERS OR CELLULOSE DERIVATIVES FOR LENSES | PILKINGTON PLC (GB) | 1996-05-28 | — | — | US | disclosed |
| WO-1995005371-A1 | PHOTOCHROMIC NAPHTHO(2,1-B)PYRANS | PILKINGTON PLC (GB) | 1995-02-23 | — | — | WO | disclosed |
| JP-H01157961-A | (6-(HETERO)ARYLOXY-NAPHTHALEN-2-YL-OXY)ALKANECARBOXYLIC ACID DERIVATIVE | BAYER AG | 1989-06-21 | — | — | JP | disclosed |