SCHEMBL991491

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7571476	0.90	KCNH2 (0.52)	KCNH2HSD17B10USP2PAK1CYP1A2
	SCHEMBL7595465	0.86	ALOX5 (0.54)	KCNH2HSD17B10USP2PAK1CYP1A2
	SCHEMBL4885527	0.84	IDO1 (0.54)	KCNH2HSD17B10USP2PAK1CYP1A2
	SCHEMBL11196561	0.81	HTR1B (0.56)	KCNH2HSD17B10USP2PAK1CYP1A2
	SCHEMBL2703781	0.81	GAA (0.53)	KCNH2CYP2C9CNR1CNR2TDP1
	SCHEMBL9870108	0.81	TSHR (0.47)	HSD17B10CYP1A2CYP2C19SLC2A1CNR1
	Ammonia Solution, Strong SCHEMBL27937782	0.79	TSHR (0.46)	HSD17B10CYP1A2CYP2C19SLC2A1CNR1
	SCHEMBL29371827	0.78	TLR8 (0.44)	CYP1A2SLC2A1CNR1CNR2TDP1
	SCHEMBL7966951	0.78	TLR8 (0.44)	CYP1A2SLC2A1CNR1CNR2TDP1
	SCHEMBL15345502	0.77	SLC2A1 (0.49)	SLC2A1CNR1CNR2KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.