Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11336774 | 0.88 | TDP1 (0.51) | MAPK1TDP1SLC1A5TRPA1CYP3A4 | |
| SCHEMBL10745186 | 0.85 | MAPK1 (0.49) | MAPK1TDP1SLC1A5TRPA1CYP3A4 | |
| SCHEMBL1555311 | 0.83 | MAPK1 (0.56) | MAPK1TDP1SLC1A5TRPA1CYP3A4 | |
| SCHEMBL11472958 | 0.82 | TDP1 (0.45) | MAPK1TDP1SLC1A5TRPA1CYP3A4 | |
| SCHEMBL9859275 | 0.79 | MAPK1 (0.54) | MAPK1TDP1SLC1A5TRPA1CYP3A4 | |
| SCHEMBL11082120 | 0.79 | MAPK1 (0.54) | MAPK1TDP1SLC1A5TRPA1CYP3A4 | |
| SCHEMBL11334967 | 0.77 | MAPK1 (0.51) | MAPK1TDP1SLC1A5TRPA1CYP3A4 | |
| SCHEMBL7575949 | 0.75 | CYP3A4 (0.36) | SLC1A5CYP3A4 | |
| SCHEMBL29873432 | 0.75 | TDP1 (0.56) | MAPK1TDP1TRPA1CYP3A4 | |
| SCHEMBL1879413 | 0.75 | TDP1 (0.56) | MAPK1TDP1TRPA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944321-B1 | COMPOSITIONS FOR THE SYSTEMIC CONTROL OF PARASITES OF WARM-BLOODED ANIMALS | ISAGRO SPA (IT) | 2002-09-18 | — | — | EP | disclosed |
| US-6136836-A | A 1-(3-CHLORO-4-(1,1,2-TRIFLUORO-2-FLUOROMETHOXYETHOXY)PHENYL-3-(2,6-DIFLUOROBENZOYL)UREA | ISAGRO S.P.A. (IT) | 2000-10-24 | — | — | US | disclosed |
| EP-0944321-A1 | COMPOSITIONS FOR THE SYSTEMIC CONTROL OF PARASITES OF WARM-BLOODED ANIMALS | ISAGRO S.p.A. (IT) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025466-A1 | COMPOSITIONS FOR THE SYSTEMIC CONTROL OF PARASITES OF WARM-BLOODED ANIMALS | ISAGRO S.P.A. (IT) | 1998-06-18 | — | — | WO | disclosed |