Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10702989 | 0.86 | PDE7A (0.41) | MEN1KMT2AMAPTKDM4ESCN9A | |
| SCHEMBL10704478 | 0.86 | PDE7A (0.39) | CYP3A4TSHRMEN1KMT2AMAPT | |
| SCHEMBL9447561 | 0.85 | MEN1 (0.44) | CYP3A4TSHRMRGPRX4MEN1KMT2A | |
| SCHEMBL28351619 | 0.83 | MEN1 (0.42) | CYP3A4TSHRMRGPRX4MEN1KMT2A | |
| SCHEMBL11307249 | 0.83 | CYP3A4 (0.39) | CYP3A4TSHRMRGPRX4MEN1KMT2A | |
| SCHEMBL236764 | 0.80 | CYP3A4 (0.46) | CYP3A4TSHRMRGPRX4CA1CA2 | |
| SCHEMBL30140163 | 0.80 | CYP3A4 (0.46) | CYP3A4TSHRMRGPRX4CA1CA2 | |
| SCHEMBL27960178 | 0.76 | PDE7A (0.45) | CYP3A4MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7706904 | 0.76 | CYP3A4 (0.36) | CYP3A4TSHRMRGPRX4MEN1KMT2A | |
| SCHEMBL7571558 | 0.75 | MAPK1 (0.45) | CYP3A4SLC1A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271923-B1 | N-(2,6-difluorobenzoyl)-N'-3-chloro-4-[1,1,2-trifluoro-2-(trifluoromethoxy) ethoxy] phenyl urea having insecticidal activity | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1990-08-22 | — | — | EP | claimed |
| EP-0271923-A1 | N-(2,6-difluorobenzoyl)-N'-3-chloro-4-[1,1,2-trifluoro-2-(trifluoromethoxy) ethoxy] phenyl urea having insecticidal activity | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1988-06-22 | — | — | EP | claimed |
| EP-0944321-B1 | COMPOSITIONS FOR THE SYSTEMIC CONTROL OF PARASITES OF WARM-BLOODED ANIMALS | ISAGRO SPA (IT) | 2002-09-18 | — | — | EP | disclosed |
| US-6136836-A | A 1-(3-CHLORO-4-(1,1,2-TRIFLUORO-2-FLUOROMETHOXYETHOXY)PHENYL-3-(2,6-DIFLUOROBENZOYL)UREA | ISAGRO S.P.A. (IT) | 2000-10-24 | — | — | US | disclosed |
| EP-0944321-A1 | COMPOSITIONS FOR THE SYSTEMIC CONTROL OF PARASITES OF WARM-BLOODED ANIMALS | ISAGRO S.p.A. (IT) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025466-A1 | COMPOSITIONS FOR THE SYSTEMIC CONTROL OF PARASITES OF WARM-BLOODED ANIMALS | ISAGRO S.P.A. (IT) | 1998-06-18 | — | — | WO | disclosed |
| EP-0271923-B1 | N-(2,6-difluorobenzoyl)-N'-3-chloro-4-[1,1,2-trifluoro-2-(trifluoromethoxy) ethoxy] phenyl urea having insecticidal activity | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1990-08-22 | — | — | EP | disclosed |
| EP-0271923-A1 | N-(2,6-difluorobenzoyl)-N'-3-chloro-4-[1,1,2-trifluoro-2-(trifluoromethoxy) ethoxy] phenyl urea having insecticidal activity | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1988-06-22 | — | — | EP | disclosed |