Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.57 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5955381 | 0.92 | STAT3 (0.60) | STAT3FFAR4KEAP1NFE2L2SQSTM1 | |
| SCHEMBL14832698 | 0.88 | FFAR4 (0.63) | STAT3FFAR4KEAP1LMNAALDH1A1 | |
| SCHEMBL5955298 | 0.86 | FFAR4 (0.71) | FFAR4KEAP1NFE2L2SQSTM1LMNA | |
| SCHEMBL7572445 | 0.86 | KEAP1 (0.59) | FFAR4KEAP1NFE2L2SQSTM1LMNA | |
| SCHEMBL7572540 | 0.84 | KMT2A (0.58) | FFAR4KEAP1NFE2L2SQSTM1LMNA | |
| SCHEMBL7577285 | 0.84 | FFAR4 (0.59) | FFAR4KEAP1NFE2L2SQSTM1LMNA | |
| SCHEMBL21708362 | 0.84 | LMNA (0.58) | STAT3FFAR4KEAP1NFE2L2SQSTM1 | |
| SCHEMBL5956219 | 0.83 | KEAP1 (0.63) | FFAR4KEAP1NFE2L2SQSTM1LMNA | |
| SCHEMBL5955235 | 0.83 | CYP2C9 (0.59) | FFAR4LMNAHTTKMT2A | |
| SCHEMBL21708341 | 0.83 | STAT3 (0.73) | STAT3KEAP1NFE2L2SQSTM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |