Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.72 |
| ▸ | FAAH | O00519 | 4/20 | 0.72 |
| ▸ | ABHD16A | O95870 | 2/20 | 0.53 |
| ▸ | LIPC | P11150 | 2/20 | 0.51 |
| ▸ | LIPE | Q05469 | 2/20 | 0.51 |
| ▸ | LPL | P06858 | 1/20 | 0.51 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045989 | 0.90 | MGLL (0.66) | MGLLFAAHABHD16ALIPCLIPE | |
| SCHEMBL7046095 | 0.87 | MGLL (0.74) | MGLLFAAHABHD16ALIPCLIPE | |
| SCHEMBL7656723 | 0.87 | MGLL (0.62) | MGLLFAAHABHD16ALIPCLIPE | |
| SCHEMBL7045977 | 0.87 | MGLL (0.62) | MGLLFAAHABHD16ALIPCLIPE | |
| SCHEMBL7656177 | 0.86 | MGLL (0.61) | MGLLFAAHABHD16ALIPCLIPE | |
| SCHEMBL6615026 | 0.86 | MGLL (0.75) | MGLLFAAHABHD16ALIPCLIPE | |
| SCHEMBL29499689 | 0.84 | MGLL (1.00) | MGLLFAAHABHD16ALIPCLIPE | |
| SCHEMBL7042914 | 0.84 | MGLL (1.00) | MGLLFAAHABHD16ALIPCLIPE | |
| SCHEMBL7046445 | 0.84 | MGLL (0.62) | MGLLFAAHABHD16ALIPCLIPE | |
| SCHEMBL7046042 | 0.83 | MGLL (0.72) | MGLLFAAHABHD16ALIPCLIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-A1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | Aventis Pharma Deutschland GmbH (DE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001066531-A1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-09-13 | — | — | WO | disclosed |