SCHEMBL7046095

SCHEMBL7046095

COc1nn(-c2ccc(NC(=O)Oc3ccccc3)c(C)c2)c(=O)o1

nearest known ligand 0.74

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 7/20 0.74
FAAH O00519 5/20 0.74
ABHD16A O95870 2/20 0.46
LIPC P11150 2/20 0.45
LIPE Q05469 2/20 0.45
LPL P06858 1/20 0.45
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GLA P06280 1/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.42
ATM Q13315 1/20 0.42
MAOB P27338 1/20 0.42
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7571649 0.87 MGLL (0.72) MGLLFAAHABHD16ALIPCLIPE
SCHEMBL7042914 0.85 MGLL (1.00) MGLLFAAHABHD16ALIPCLIPE
SCHEMBL6615026 0.82 MGLL (0.75) MGLLFAAHABHD16ALIPCLIPE
SCHEMBL7045989 0.82 MGLL (0.66) MGLLFAAHABHD16ALIPCLIPE
SCHEMBL6601577 0.81 MGLL (0.58) MGLLFAAHABHD16ALIPCLIPE
SCHEMBL7046148 0.81 MGLL (0.78) MGLLFAAHABHD16ALIPCLIPE
SCHEMBL7046042 0.80 MGLL (0.72) MGLLFAAHABHD16ALIPCLIPE
SCHEMBL6602881 0.80 MGLL (0.68) MGLLFAAHKDM4EALDH1A1GAA
SCHEMBL7656723 0.79 MGLL (0.62) MGLLFAAHABHD16ALIPCLIPE
SCHEMBL6599507 0.79 MGLL (0.57) MGLLFAAHABHD16ALIPCLIPE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030236288-A1 Use of substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadizol-2-ones for inhibiting pancreatic lipase AVENTIS PHARMA DEUTSCHLAND GMBH 2003-12-25 US disclosed
US-6369088-B2 ANTIDIABETIC AGENTS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-04-09 US disclosed
US-20010031772-A1 Substituted 3-phenyl-5-alkoxy-1,3,4-oxadiazol-2-ones, their preparation and their use as pharmaceuticals SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031772-A1 Substituted 3-phenyl-5-alkoxy-1,3,4-oxadiazol-2-ones, their preparation and their use as pharmaceuticals CNR1, PTGER1, CNR2 MGLL 1542/4885FAAH 46/4885ABHD16A 1922/4885
US-20030236288-A1 Use of substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadizol-2-ones for inhibiting pancreatic lipase PNLIP, CEL, LIPE MGLL 10/4885FAAH 142/4885ABHD16A 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.