Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778479 | 0.98 | MAOB (0.56) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL9778622 | 0.94 | MAOB (0.59) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL9778453 | 0.88 | MAOB (0.54) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL9778680 | 0.85 | MAOB (0.51) | MAOBLMNACYP1A2CYP2C19RAB9A | |
| SCHEMBL9778501 | 0.85 | NPC1 (0.51) | MAOBLMNARAB9AMAOALTA4H | |
| SCHEMBL9778819 | 0.85 | MAPT (0.51) | MAOBLMNARAB9AMAOAMAPT | |
| SCHEMBL9778518 | 0.85 | RXRA (0.47) | MAOBLMNARAB9AMAPTL3MBTL1 | |
| SCHEMBL9778533 | 0.85 | APP (0.51) | MAOBLMNARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9778594 | 0.85 | MAOB (0.51) | MAOBRAB9AMAOAMAPTHRH3 | |
| SCHEMBL9778797 | 0.84 | MAOB (0.47) | MAOBLMNARAB9AMAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3049401-B1 | POLYMER-FIXED DERIVATIVES OF DITHIOLANE OR DITHIANE | KARLSRUHER INST TECHNOLOGIE (DE) | 2018-11-07 | — | — | EP | disclosed |
| US-9518039-B2 | Polymer-fixed derivatives of dithiolane or dithiane | KARLSRUHER INSTITUT FUER TECHNOLOGIE (DE) | 2016-12-13 | — | — | US | disclosed |
| US-20160229832-A1 | POLYMER-FIXED DERIVATIVES OF DITHIOLANE OR DITHIANE | KARLSRUHER INSTITUT FUER TECHNOLOGIE (DE) | 2016-08-11 | — | — | US | disclosed |
| EP-0873992-B1 | Indene compounds having activity as SERMs | LILLY CO ELI (US) | 2002-09-25 | — | — | EP | disclosed |
| US-5994370-A | ESTROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 1999-11-30 | — | — | US | disclosed |
| WO-1998048806-A1 | INDENE COMPOUNDS HAVING ACTIVITY AS SERMS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| EP-0873992-A1 | Indene compounds having activity as SERMs | ELI LILLY AND COMPANY (US) | 1998-10-28 | — | — | EP | disclosed |
| US-5063197-A | Aromatic compound | MITSUBISHI PAPER MILLS LIMITED (JP) | 1991-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229832-A1 | POLYMER-FIXED DERIVATIVES OF DITHIOLANE OR DITHIANE | TCP1, ALG1, DDAH1 | MAOB 2078/4885LMNA 3019/4885CYP1A2 1918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.