Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204492 | 0.79 | NOS1 (0.53) | NOS1CHEK1DYRK1ACHUKTDO2 | |
| SCHEMBL7572921 | 0.76 | MAPT (0.47) | NOS1CHEK1MAPTKDM4EMEN1 | |
| SCHEMBL19204860 | 0.76 | NOS1 (0.46) | NOS1DYRK1ATDO2HRH4FGFR1 | |
| SCHEMBL2430496 | 0.76 | NOS1 (0.50) | NOS1CHEK1DYRK1ATDO2MAPT | |
| SCHEMBL202508 | 0.76 | NOS1 (0.46) | NOS1DYRK1ATDO2MAPTKDM4E | |
| SCHEMBL23185496 | 0.73 | BTK (0.57) | NOS1CHEK1DYRK1ACHUKTDO2 | |
| SCHEMBL27139677 | 0.73 | NOS1 (0.57) | NOS1CHUKMAPTKDM4EMEN1 | |
| SCHEMBL759126 | 0.72 | NOS1 (0.50) | NOS1CHEK1DYRK1AMAPTKDM4E | |
| SCHEMBL23434901 | 0.72 | NOS1 (0.42) | NOS1DYRK1ATDO2MAPTKDM4E | |
| SCHEMBL23434988 | 0.72 | TDO2 (0.43) | NOS1CHEK1DYRK1ATDO2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904769-B1 | Keratin fibre dye compositions containing Indazole amine derivatives and dyeing method | OREAL (FR) | 2002-09-25 | — | — | EP | claimed |
| CN-118359634-A | Pyrazole derivative and medical use thereof | 正大天晴药业集团股份有限公司 | 2024-07-19 | — | — | CN | disclosed |
| US-6027538-A | OXIDATION DYEING OF KERATINOUS FIBERS CONTAINING AT LEAST ONE COUPLER SELECTED FROM INDAZOLEAMINE DERIVATIVES AND AT LEAST ONE OXIDATION BASE; POWERFUL, NOT VERY SELECTIVE HAIR DYES WHICH ARE CAPABLE OF GENERATING INTENSE COLOR | L'OREAL S.A. (FR) | 2000-02-22 | — | — | US | disclosed |