Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567055 | 0.88 | HDAC1 (0.54) | RAD52HDAC1HDAC6SIGMAR1TMEM97 | |
| SCHEMBL7568106 | 0.88 | SIGMAR1 (0.51) | RAD52SIGMAR1TMEM97KDM4EALDH1A1 | |
| SCHEMBL7566347 | 0.86 | HDAC1 (0.67) | RAD52HDAC1HDAC6SIGMAR1TMEM97 | |
| SCHEMBL7568080 | 0.83 | AOX1 (0.62) | RAD52HDAC1HDAC6SIGMAR1TMEM97 | |
| SCHEMBL7566167 | 0.83 | AOX1 (0.55) | RAD52HDAC1HDAC6SIGMAR1TMEM97 | |
| SCHEMBL14440618 | 0.81 | HDAC1 (0.61) | RAD52HDAC1HDAC6SIGMAR1TMEM97 | |
| SCHEMBL7564772 | 0.81 | RAD52 (0.78) | RAD52HDAC1HDAC6SIGMAR1TMEM97 | |
| SCHEMBL7569011 | 0.78 | RAD52 (0.59) | RAD52HDAC1HDAC6SIGMAR1TMEM97 | |
| SCHEMBL7567270 | 0.78 | RAD52 (0.61) | RAD52HDAC1HDAC6SIGMAR1TMEM97 | |
| SCHEMBL7571933 | 0.77 | SIGMAR1 (0.55) | RAD52HDAC1HDAC6SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |