Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL403998 | 1.00 | USP2 (0.53) | USP2SLCO1B1PAX8PDE4ALMNA | |
| Acetic Acid SCHEMBL8370700 | 1.00 | USP2 (0.53) | USP2SLCO1B1PAX8PDE4ALMNA | |
| Acetic Acid SCHEMBL489053 | 1.00 | USP2 (0.53) | USP2SLCO1B1PAX8PDE4ALMNA | |
| Pyruvate SCHEMBL17296438 | 0.94 | USP2 (0.48) | USP2SLCO1B1PAX8PDE4ALMNA | |
| Bicarbonate SCHEMBL20888 | 0.94 | USP2 (0.55) | USP2SLCO1B1PAX8PDE4ALMNA | |
| SCHEMBL2227363 | 0.92 | LMNA (0.52) | USP2SLCO1B1PAX8PDE4ALMNA | |
| SCHEMBL8586304 | 0.92 | LMNA (0.52) | USP2SLCO1B1PAX8PDE4ALMNA | |
| SCHEMBL420278 | 0.92 | LMNA (0.52) | USP2SLCO1B1PAX8PDE4ALMNA | |
| SCHEMBL1548302 | 0.92 | LMNA (0.52) | USP2SLCO1B1PAX8PDE4ALMNA | |
| SCHEMBL22963142 | 0.92 | LMNA (0.52) | USP2SLCO1B1PAX8PDE4ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020192231-A1 | Method of increasing anti-neuGc antibody levels in blood | IMMUCOM INC. | 2002-12-19 | — | — | US | claimed |
| WO-2002094199-A2 | METHOD OF INCREASING ANTI-NeuGc ANTIBODY LEVELS IN BLOOD | IMMUCOM INC. (US) | 2002-11-28 | — | — | WO | claimed |
| WO-2000007602-A1 | COMPOUNDS FOR ALTERING CELL SURFACE SIALIC ACIDS AND METHODS OF USE THEREFOR | THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2000-02-17 | — | — | WO | disclosed |