Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7572044 | 0.94 | USP2 (0.53) | USP2SLCO1B1PDE4APAX8LMNA | |
| Acetic Acid SCHEMBL489053 | 0.94 | USP2 (0.53) | USP2SLCO1B1PDE4APAX8LMNA | |
| Acetic Acid SCHEMBL8370700 | 0.94 | USP2 (0.53) | USP2SLCO1B1PDE4APAX8LMNA | |
| Acetic Acid SCHEMBL403998 | 0.94 | USP2 (0.53) | USP2SLCO1B1PDE4APAX8LMNA | |
| SCHEMBL2228073 | 0.94 | LMNA (0.52) | USP2SLCO1B1PDE4APAX8LMNA | |
| SCHEMBL1548302 | 0.94 | LMNA (0.52) | USP2SLCO1B1PDE4APAX8LMNA | |
| SCHEMBL8586304 | 0.94 | LMNA (0.52) | USP2SLCO1B1PDE4APAX8LMNA | |
| SCHEMBL420278 | 0.94 | LMNA (0.52) | USP2SLCO1B1PDE4APAX8LMNA | |
| SCHEMBL22963142 | 0.94 | LMNA (0.52) | USP2SLCO1B1PDE4APAX8LMNA | |
| SCHEMBL17493340 | 0.94 | LMNA (0.52) | USP2SLCO1B1PDE4APAX8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10857176-B2 | Composition comprising polyglucosamine-glyoxylate solutions mixed with hyaluronan | Oligo Médic Inc. (CA) | 2020-12-08 | — | — | US | claimed |
| US-20190247421-A1 | COMPOSITION COMPRISING POLYGLUCOSAMINE-GLYOXYLATE SOLUTIONS MIXED WITH HYALURONAN | OLIGO MEDIC INC. | 2019-08-15 | — | — | US | claimed |
| CN-103189435-B | Highly biocompatible dual thermogelling chitosan/glucosamine salt compositions | OLIGO MEDIC INC. (CA) | 2016-02-17 | — | — | CN | claimed |
| EP-2609149-B1 | HIGHLY BIOCOMPATIBLE DUAL THERMOGELLING CHITOSAN/GLUCOSAMINE SALT COMPOSITIONS | OLIGO MEDIC INC (CA) | 2015-08-12 | — | — | EP | claimed |
| US-8784850-B2 | Highly biocompatible dual thermogelling chitosan/glucosamine salt composition | OLIGO MEDIC INC (CA) | 2014-07-22 | — | — | US | claimed |
| US-20130266549-A1 | HIGHLY BIOCOMPATIBLE DUAL THERMOGELLING CHITOSAN/GLUCOSAMINE SALT COMPOSITION | OLIGO MEDIC INC (CA) | 2013-10-10 | — | — | US | claimed |
| US-8506972-B2 | Highly biocompatible dual thermogelling chitosan/glucosamine salt compositions | OLIGO MEDIC INC (CA) | 2013-08-13 | — | — | US | claimed |
| EP-2609149-A1 | HIGHLY BIOCOMPATIBLE DUAL THERMOGELLING CHITOSAN/GLUCOSAMINE SALT COMPOSITIONS | Oligo Medic Inc. (CA) | 2013-07-03 | — | — | EP | claimed |
| CN-103189435-A | Highly biocompatible dual thermogelling chitosan/glucosamine salt compositions | OLIGO MEDIC INC | 2013-07-03 | — | — | CN | claimed |
| US-20120052012-A1 | HIGHLY BIOCOMPATIBLE DUAL THERMOGELLING CHITOSAN/GLUCOSAMINE SALT COMPOSITIONS | OLIGO MEDIC INC. (CA) | 2012-03-01 | — | — | US | claimed |
| WO-2012024785-A1 | HIGHLY BIOCOMPATIBLE DUAL THERMOGELLING CHITOSAN/GLUCOSAMINE SALT COMPOSITIONS | OLIGO MEDIC INC. (CA) | 2012-03-01 | — | — | WO | claimed |
| US-10857176-B2 | Composition comprising polyglucosamine-glyoxylate solutions mixed with hyaluronan | Oligo Médic Inc. (CA) | 2020-12-08 | — | — | US | disclosed |
| US-20190247421-A1 | COMPOSITION COMPRISING POLYGLUCOSAMINE-GLYOXYLATE SOLUTIONS MIXED WITH HYALURONAN | OLIGO MEDIC INC. | 2019-08-15 | — | — | US | disclosed |
| US-20170216341-A1 | COMPOSITION COMPRISING POLYGLUCOSAMINE-GLYOXYLATE SOLUTIONS MIXED WITH HYALURONAN | OLIGO MÉDIC INC (CA) | 2017-08-03 | — | — | US | disclosed |
| CN-103189435-B | Highly biocompatible dual thermogelling chitosan/glucosamine salt compositions | OLIGO MEDIC INC. (CA) | 2016-02-17 | — | — | CN | disclosed |
| CN-102415596-A | Carbonated beverage | UNIV NINGBO | 2012-04-18 | — | — | CN | disclosed |
| US-20120052012-A1 | HIGHLY BIOCOMPATIBLE DUAL THERMOGELLING CHITOSAN/GLUCOSAMINE SALT COMPOSITIONS | OLIGO MEDIC INC. (CA) | 2012-03-01 | — | — | US | disclosed |
| WO-2012024785-A1 | HIGHLY BIOCOMPATIBLE DUAL THERMOGELLING CHITOSAN/GLUCOSAMINE SALT COMPOSITIONS | OLIGO MEDIC INC. (CA) | 2012-03-01 | — | — | WO | disclosed |
| US-6589555-B2 | Effervescent vitaceutical compositions and related methods | PANDYA MAHENDRA (US) | 2003-07-08 | — | — | US | disclosed |
| US-20010051134-A1 | Effervescent vitaceutical compositions and related methods | PANDYA MAHENDRA (US) | 2001-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10857176-B2 | Composition comprising polyglucosamine-glyoxylate solutions mixed with hyaluronan | CD44, IDUA, FUT6 | USP2 628/4885SLCO1B1 1828/4885PDE4A 4358/4885 |
| US-20170216341-A1 | COMPOSITION COMPRISING POLYGLUCOSAMINE-GLYOXYLATE SOLUTIONS MIXED WITH HYALURONAN | CD44, IDUA, FUT6 | USP2 628/4885SLCO1B1 1828/4885PDE4A 4358/4885 |
| US-20190247421-A1 | COMPOSITION COMPRISING POLYGLUCOSAMINE-GLYOXYLATE SOLUTIONS MIXED WITH HYALURONAN | CD44, IDUA, FUT6 | USP2 628/4885SLCO1B1 1828/4885PDE4A 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.