Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CDH1 | P12830 | 1/20 | 0.42 |
| ▸ | APC | P25054 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565784 | 1.00 | ALDH1A1 (0.71) | ALDH1A1PIM1PIM2CYP2C9PTGES | |
| Phenazine-1-Carboxylic Acid SCHEMBL27884214 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP2C9HPGDHSD17B10NQO2 | |
| Phenazine-1-Carboxylic Acid SCHEMBL28160016 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP2C9HPGDHSD17B10NQO2 | |
| Phenazine-1-Carboxylic Acid SCHEMBL122864 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP2C9HPGDHSD17B10NQO2 | |
| Phenazine-1-Carboxylic Acid SCHEMBL29370801 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP2C9HPGDHSD17B10NQO2 | |
| SCHEMBL5696607 | 0.83 | ALDH1A1 (0.73) | ALDH1A1CYP2C9HPGDMEN1KMT2A | |
| SCHEMBL8187609 | 0.83 | ALDH1A1 (0.73) | ALDH1A1CYP2C9HPGDMEN1KMT2A | |
| SCHEMBL29337447 | 0.83 | ALDH1A1 (0.73) | ALDH1A1PIM1CYP2C9ALOX5NQO2 | |
| SCHEMBL29337448 | 0.83 | ALDH1A1 (0.73) | ALDH1A1PIM1CYP2C9ALOX5NQO2 | |
| Phenazine-1-Carboxylic Acid SCHEMBL28714733 | 0.82 | ALDH1A1 (0.96) | ALDH1A1CYP2C9HPGDHSD17B10NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |