Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8187609 | 1.00 | ALDH1A1 (0.73) | ALDH1A1TDP1RAB9ANPC1HPGD | |
| SCHEMBL8180213 | 0.88 | ALDH1A1 (0.69) | ALDH1A1TDP1RAB9ANPC1HPGD | |
| Phenazine-1-Carboxylic Acid SCHEMBL27884214 | 0.85 | ALDH1A1 (1.00) | ALDH1A1RAB9AHPGDGAAKDM4E | |
| Phenazine-1-Carboxylic Acid SCHEMBL29370801 | 0.85 | ALDH1A1 (1.00) | ALDH1A1RAB9AHPGDGAAKDM4E | |
| Phenazine-1-Carboxylic Acid SCHEMBL28160016 | 0.85 | ALDH1A1 (1.00) | ALDH1A1RAB9AHPGDGAAKDM4E | |
| Phenazine-1-Carboxylic Acid SCHEMBL122864 | 0.85 | ALDH1A1 (1.00) | ALDH1A1RAB9AHPGDGAAKDM4E | |
| SCHEMBL29337447 | 0.84 | ALDH1A1 (0.73) | ALDH1A1TDP1RAB9AGAAKDM4E | |
| SCHEMBL29337448 | 0.84 | ALDH1A1 (0.73) | ALDH1A1TDP1RAB9AGAAKDM4E | |
| SCHEMBL7324112 | 0.84 | KMT2A (0.61) | ALDH1A1TDP1RAB9ANPC1HPGD | |
| SCHEMBL16023857 | 0.84 | KMT2A (0.61) | ALDH1A1TDP1RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891182-B1 | ENZYME ASSISTED DYEING OF KERATINOUS FIBRES | NOVOZYMES AS (DK) | 2001-11-14 | — | — | EP | claimed |
| EP-0863950-B1 | HAIR DYEING COMPOSITION | NOVOZYMES AS (DK) | 2001-10-10 | — | — | EP | claimed |
| EP-0865465-B1 | LACCASES WITH IMPROVED DYEING PROPERTIES | NOVOZYMES AS (DK) | 2001-05-30 | — | — | EP | claimed |
| EP-0865465-A1 | LACCASES WITH IMPROVED DYEING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-09-23 | — | — | EP | claimed |
| EP-0863950-A1 | AN ENZYME FOR DYING KERATINOUS FIBRES | NOVO NORDISK A/S (DK) | 1998-09-16 | — | — | EP | claimed |
| WO-1997019998-A1 | AN ENZYME FOR DYING KERATINOUS FIBRES | NOVO NORDISK A/S (DK) | 1997-06-05 | — | — | WO | claimed |
| WO-1997019999-A1 | LACCASES WITH IMPROVED DYEING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-06-05 | — | — | WO | claimed |
| EP-0973875-B1 | STORAGE-STABLE LIQUID FORMULATION COMPRISING A LACCASE | NOVOZYMES AS (DK) | 2006-06-14 | — | — | EP | disclosed |
| EP-1137391-B1 | METHOD FOR TREATING HAIR | NOVOZYMES AS (DK) | 2004-11-03 | — | — | EP | disclosed |
| US-6667167-B1 | Containing a polyalcohol such as a polyoxyalkylene glycol or ether, and a mono-, di-, oligo- or polysaccharides; pH that is more alkaline than the pH optimum of the laccase. | NOVOZYMES A/S (DK) | 2003-12-23 | — | — | US | disclosed |
| US-6572843-B1 | Combining permanent dyeing and straightening; applying to reduced hair an oxidizing enzyme (Laccase), a mediator, and a chemical oxidizing agent that produces hydrogen peroxide | NOVOZYMES, A/S (DK) | 2003-06-03 | — | — | US | disclosed |
| EP-1076494-B1 | RE-FORMATION OF KERATINOUS FIBRE CROSS LINKS | NOVOZYMES AS (DK) | 2002-09-18 | — | — | EP | disclosed |
| US-20020007524-A1 | Contacting fibers in a dry state with an oxidoreductase and a dye precursor; reduced hair damage | NOVOZYMES A/S (DK) | 2002-01-24 | — | — | US | disclosed |
| US-6001134-A | PERMANENT HAIR DYE | NOVO NORDISK A/S (DK) | 1999-12-14 | — | — | US | disclosed |
| WO-1999058013-A1 | RE-FORMATION OF KERATINOUS FIBRE CROSS LINKS | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | disclosed |
| US-5948121-A | PERMANENT DYEING OF KERATINOUS FIBERS. LACCASE DERIVED FROM A STRAIN OF THE GENUS MYCELIOPHTHORA | NOVO NORDISK A/S (DK) | 1999-09-07 | — | — | US | disclosed |
| US-5899212-A | CLEAVAGE OF DISULFIDE BONDS, OXIDOREDUCTASE | NOVO NORDISK A/S (DK) | 1999-05-04 | — | — | US | disclosed |
| WO-1999015137-A1 | ENZYMATIC FOAM COMPOSITIONS FOR DYEING KERATINOUS FIBRES | NOVO NORDISK A/S (DK) | 1999-04-01 | — | — | WO | disclosed |
| EP-0891182-A1 | AN ENZYME FOR DYEING KERATINOUS FIBRES | NOVO NORDISK A/S (DK) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997037633-A1 | AN ENZYME FOR DYEING KERATINOUS FIBRES | NOVO NORDISK A/S (DK) | 1997-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007524-A1 | Contacting fibers in a dry state with an oxidoreductase and a dye precursor; reduced hair damage | KRT18, CYB5R3, ADH7 | ALDH1A1 169/4885TDP1 949/4885RAB9A 4688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.