Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5916593 | 1.00 | ACHE (0.46) | ACHEEPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL5916808 | 0.98 | ACHE (0.46) | ACHEEPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL5916622 | 0.93 | ACHE (0.47) | ACHEEPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL5916820 | 0.88 | EPHX1 (0.59) | ACHEEPHX1 | |
| SCHEMBL5916591 | 0.87 | EPHX1 (0.49) | ACHEEPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL5916674 | 0.87 | EPHX1 (0.49) | ACHEEPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL5916877 | 0.86 | EPHX1 (0.56) | ACHEEPHX1 | |
| SCHEMBL5916503 | 0.86 | KMT2A (0.41) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5916614 | 0.85 | ACHE (0.47) | ACHEEPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL5916566 | 0.85 | ACHE (0.47) | ACHEEPHX1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002050020-A1 | METHOD FOR PRODUCING ISOCYANATES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-06-27 | — | — | WO | disclosed |