Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL724028 | 0.88 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL29873191 | 0.88 | — | — | |
| Propylene Glycol SCHEMBL161401 | 0.88 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL3535 | 0.88 | — | — | |
| Propylene Glycol SCHEMBL55583 | 0.88 | — | — | |
| Propylene Glycol SCHEMBL15864609 | 0.88 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL28578 | 0.88 | — | — | |
| Propylene Glycol SCHEMBL7522896 | 0.88 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL25230484 | 0.84 | — | — | |
| Propylene Glycol SCHEMBL11347249 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024091839-A1 | COATING COMPOSITION FOR USE IN HIGH EFFICIENCY APPLICATORS | PPG INDUSTRIES OHIO, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
| US-20230374314-A1 | HIGH TRANSFER EFFICIENCY APPLICATION METHODS AND SHEAR THINNING COATING COMPOSITIONS FOR APPLICATION USING THE METHODS | PPG INDUSTRIES OHIO, INC. (US) | 2023-11-23 | — | — | US | disclosed |
| EP-4225855-A1 | HIGH TRANSFER EFFICIENCY APPLICATION METHODS AND SHEAR THINNING COATING COMPOSITIONS FOR APPLICATION USING THE METHODS | PPG Industries Ohio Inc. (US) | 2023-08-16 | — | — | EP | disclosed |
| CN-106139155-A | The pharmaceutical carrier of slow-release | 钟术光 | 2016-11-23 | — | — | CN | disclosed |
| CN-105854022-A | Drug carrier capable of slowly releasing drug | 钟术光 | 2016-08-17 | — | — | CN | disclosed |
| CN-102698277-B | Drug carrier for sustained release of drug | 钟术光 | 2016-08-03 | — | — | CN | disclosed |
| CN-102000335-B | Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base | JANSSEN PHARMACEUTICA N.V. (BE) | 2014-10-29 | — | — | CN | disclosed |
| CN-102698277-A | Drug carrier for sustained release of drug | SHUGUANG ZHONG | 2012-10-03 | — | — | CN | disclosed |
| CN-102000335-A | Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base | JANSSEN PHARMACEUTICA NV | 2011-04-06 | — | — | CN | disclosed |
| CN-1720027-A | Pharmaceutical composition comprising a basic or acidic pharmaceutical compound, a surfactant and a physiologically acceptable water-soluble acid or base | JANSSEN PHARMACEUTICA NV (BE) | 2006-01-11 | — | — | CN | disclosed |
| EP-1237532-A2 | ULTRAVIOLET RADIATION ABSORBING WAXES USEFUL IN COSMETIC COMPOSITIONS | The C.P. Hall Company (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001041715-A2 | ULTRAVIOLET RADIATION ABSORBING WAXES USEFUL IN COSMETIC COMPOSITIONS | THE C.P. HALL COMPANY (US) | 2001-06-14 | — | — | WO | disclosed |
| EP-0097583-A2 | Aluminum corrosion inhibitor composition comprising a graft copolymer and a silicate | UNION CARBIDE CORPORATION (US) | 1984-01-04 | — | — | EP | disclosed |
| US-4404114-A | AQUEOUS OR ALCOHOLIC SOLUTION OF AN UNSATURATED ACID-POLYETHER GRAFT POLYMER AND A SILICATE; SOLAR CELLS; INTERNAL COMBUSTION ENGINES | UNION CARBIDE CORPORATION (US) | 1983-09-13 | — | — | US | disclosed |
| US-4256873-A | CATALYTICALLY REACTING FINE SILICA AND A POLYHYDROXIDE TO PRODUCE AN ORGANIC HYDROXY SILICATE WHICH CAN MODIFY RESINS OF POLYURETHANE, -ESTERS, ETHERS, AND ADDITION POLYMERS; TOUGH PROTECTIVE COATINGS; FOAMS | BLOUNT DAVID H | 1981-03-17 | — | — | US | disclosed |
| US-4153768-A | Organic hydroxy silicates utilized as curing agents for polyurethane prepolymers | BLOUNT DAVID H | 1979-05-08 | — | — | US | disclosed |
| US-4139549-A | Process for the production of organic hydroxy silicate compounds and their condensation products | BLOUNT DAVID H | 1979-02-13 | — | — | US | disclosed |
| US-4089883-A | Process for the production of organic hydroxy silicate compounds and their condensation products | BLOUNT DAVID H | 1978-05-16 | — | — | US | disclosed |