Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 12/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7577310 | 0.85 | PTGES2 (0.53) | PTGES2ALDH1A1HTTKMT2APKM | |
| SCHEMBL17627099 | 0.81 | KMT2A (0.55) | PTGES2ALDH1A1HTTKMT2APKM | |
| SCHEMBL16290226 | 0.80 | KMT2A (0.54) | PTGES2ALDH1A1HTTKMT2APKM | |
| SCHEMBL13561005 | 0.74 | KMT2A (0.60) | PTGES2ALDH1A1HTTKMT2APKM | |
| SCHEMBL3780936 | 0.74 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3780942 | 0.74 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL1122431 | 0.73 | KMT2A (0.77) | PTGES2ALDH1A1HTTKMT2APKM | |
| SCHEMBL1122427 | 0.73 | KMT2A (0.77) | PTGES2ALDH1A1HTTKMT2APKM | |
| SCHEMBL7590242 | 0.73 | PTGES2 (0.57) | PTGES2ALDH1A1HTTKMT2APKM | |
| SCHEMBL7590246 | 0.73 | PTGES2 (0.57) | PTGES2ALDH1A1HTTKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |