Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 18/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572234 | 0.85 | PTGES2 (0.58) | PTGES2ALDH1A1HTTPKMKMT2A | |
| SCHEMBL7572303 | 0.74 | KMT2A (0.47) | ALDH1A1KMT2A | |
| SCHEMBL17627099 | 0.73 | KMT2A (0.55) | PTGES2ALDH1A1HTTPKMKMT2A | |
| SCHEMBL16290226 | 0.72 | KMT2A (0.54) | PTGES2ALDH1A1HTTPKMKMT2A | |
| SCHEMBL1122341 | 0.70 | KMT2A (0.64) | PTGES2ALDH1A1HTTPKMKMT2A | |
| SCHEMBL10622905 | 0.70 | CA2 (0.61) | — | |
| SCHEMBL3782567 | 0.69 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3782562 | 0.69 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3777955 | 0.68 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3777953 | 0.68 | PTGES2 (1.00) | PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |