Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 10/20 | 0.66 |
| ▸ | ACE | P12821 | 8/20 | 0.66 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | NMBR | P28336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572242 | 1.00 | MME (0.66) | MMEACEHRH4TACR1CPA1 | |
| SCHEMBL8446385 | 0.96 | MME (0.60) | MMEACEHRH4TACR1CPA1 | |
| SCHEMBL7567827 | 0.91 | MME (0.73) | MMEACEHRH4CPA1ACE2 | |
| SCHEMBL7567832 | 0.91 | MME (0.73) | MMEACEHRH4CPA1ACE2 | |
| SCHEMBL7568400 | 0.89 | MME (0.52) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL7568408 | 0.89 | MME (0.52) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL27446785 | 0.89 | MME (0.80) | MMEACEHRH4TACR1CPA1 | |
| SCHEMBL8027391 | 0.89 | MME (0.80) | MMEACEHRH4TACR1CPA1 | |
| SCHEMBL7573635 | 0.87 | MME (0.55) | MMEACECPA1ACE2 | |
| SCHEMBL7573628 | 0.87 | MME (0.55) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |