Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.60 |
| ▸ | ACE | P12821 | 7/20 | 0.60 |
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | NMBR | P28336 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572248 | 0.96 | MME (0.66) | MMEACETACR1HRH4KMT2A | |
| SCHEMBL7572242 | 0.96 | MME (0.66) | MMEACETACR1HRH4KMT2A | |
| SCHEMBL8453051 | 0.88 | MME (0.47) | MMEACETACR1KMT2AKDM4E | |
| SCHEMBL7567827 | 0.87 | MME (0.73) | MMEACEHRH4KMT2ASIGMAR1 | |
| SCHEMBL7567832 | 0.87 | MME (0.73) | MMEACEHRH4KMT2ASIGMAR1 | |
| SCHEMBL8453091 | 0.86 | MME (0.48) | MMEACETACR1KMT2ACPA1 | |
| SCHEMBL7568400 | 0.86 | MME (0.52) | MMEACEKMT2AMMP2CPA1 | |
| SCHEMBL7568408 | 0.86 | MME (0.52) | MMEACEKMT2AMMP2CPA1 | |
| SCHEMBL27464501 | 0.86 | MME (0.68) | MMEACETACR1HRH4REN | |
| SCHEMBL27464096 | 0.86 | MME (0.68) | MMEACETACR1HRH4REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |