SCHEMBL757236

SCHEMBL757236

O=C(O)CC(Sc1nc2cc(Cl)ccc2s1)C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 17/20 0.76
SMN1; SMN2 Q16637 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
ALOX5 P09917 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6881379 0.94 PPARA (0.69) PPARASMN1; SMN2
SCHEMBL8972429 0.90 PPARA (0.62) PPARA
SCHEMBL5946418 0.88 PPARA (0.84) PPARASMN1; SMN2NPSR1ALOX5
SCHEMBL8972533 0.85 PPARA (0.59) PPARA
SCHEMBL8972964 0.85 PPARA (0.56) PPARASMN1; SMN2ALOX5
SCHEMBL9443367 0.83 PPARA (0.54) PPARASMN1; SMN2ALOX5
SCHEMBL9304890 0.82 PPARA (0.71) PPARASMN1; SMN2
SCHEMBL9305853 0.82 PPARA (0.53) PPARAALOX5
SCHEMBL9306667 0.82 PPARA (0.57) PPARA
SCHEMBL9443207 0.82 PPARA (0.56) PPARAALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US claimed
EP-1465935-B1 PIGMENT COMPOSITIONS WITH MODIFIED ATRP COPOLYMER DISPERSANTS BASF SE (DE) 2016-09-07 EP disclosed
EP-1611197-B1 LIGHT STABILISING POLYMER DISPERSANTS IN PIGMENT DISPERSIONS BASF SE (DE) 2012-03-21 EP disclosed
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-20060229407-A1 Light stabilising polymer dispersants in pigment dispersions CIBA SPECIALTY CHEMICALS CORP. 2006-10-12 US disclosed
US-20060160940-A1 Process for intercalating natural or szynthetic clays with block or comb copolymers CIBA SPECIALTY CHEMICALS CORP. 2006-07-20 US disclosed
US-6849679-B2 Pigment compositions with modified block copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-02-01 US disclosed
US-5549847-A STIRRING A FILTER CAKE OF CORROSION INHIBITOR WITH DISPERSANT AND THICKENER; STORAGE STABILITY CIBA-GEIGY CORPORATION (US) 1996-08-27 US disclosed
US-5347008-A Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents CIBA-GEIGY CORPORATION (US) 1994-09-13 US disclosed
EP-0375614-B1 CORROSION-INHIBITING COATING COMPOSITIONS CIBA-GEIGY AG (CH) 1993-03-31 EP disclosed
US-5198482-A Benzothiazole carboxylic acid amine salt CIBA-GEIGY CORPORATION (US) 1993-03-30 US disclosed
US-5152929-A Corrosion inhibitors for water systems CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed
EP-0375614-A1 Corrosion-inhibiting coating compositions CIBA-GEIGY AG (CH) 1990-06-27 EP disclosed
US-4612049-A BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID CIBA-GEIGY CORPORATION (US) 1986-09-16 US disclosed