Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972971 | 0.91 | PPARA (0.64) | PPARANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8972533 | 0.84 | PPARA (0.59) | PPARAALDH1A1DYRK1A | |
| SCHEMBL8972964 | 0.82 | PPARA (0.56) | PPARANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL757236 | 0.82 | PPARA (0.76) | PPARASMN1; SMN2 | |
| SCHEMBL9443207 | 0.81 | PPARA (0.56) | PPARAALDH1A1 | |
| SCHEMBL9306249 | 0.80 | PPARA (0.54) | PPARANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9443367 | 0.80 | PPARA (0.54) | PPARANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9305807 | 0.80 | PPARA (0.82) | PPARANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9443185 | 0.80 | PPARA (0.54) | PPARADYRK1A | |
| SCHEMBL10643855 | 0.79 | PPARA (0.58) | PPARANPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0375614-B1 | CORROSION-INHIBITING COATING COMPOSITIONS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | disclosed |
| US-5198482-A | Benzothiazole carboxylic acid amine salt | CIBA-GEIGY CORPORATION (US) | 1993-03-30 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0375614-A1 | Corrosion-inhibiting coating compositions | CIBA-GEIGY AG (CH) | 1990-06-27 | — | — | EP | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |