Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.46 |
| ▸ | AKR1A1 | P14550 | 3/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811061 | 0.88 | PPARA (0.58) | PPARAALOX5PPARGDYRK1AAKR1B1 | |
| SCHEMBL757236 | 0.82 | PPARA (0.76) | PPARAALOX5 | |
| SCHEMBL8972964 | 0.82 | PPARA (0.56) | PPARAALOX5PPARGPTGES | |
| SCHEMBL8972533 | 0.82 | PPARA (0.59) | PPARADYRK1A | |
| SCHEMBL9443367 | 0.80 | PPARA (0.54) | PPARAALOX5PPARGPTGES | |
| SCHEMBL9443207 | 0.79 | PPARA (0.56) | PPARAALOX5 | |
| SCHEMBL9306667 | 0.79 | PPARA (0.57) | PPARA | |
| SCHEMBL9304890 | 0.79 | PPARA (0.71) | PPARADYRK1A | |
| SCHEMBL402778 | 0.79 | ALDH1A1 (0.57) | PPARAALOX5 | |
| SCHEMBL9306249 | 0.78 | PPARA (0.54) | PPARAALOX5PPARGPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0375614-B1 | CORROSION-INHIBITING COATING COMPOSITIONS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | disclosed |
| US-5198482-A | Benzothiazole carboxylic acid amine salt | CIBA-GEIGY CORPORATION (US) | 1993-03-30 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0375614-A1 | Corrosion-inhibiting coating compositions | CIBA-GEIGY AG (CH) | 1990-06-27 | — | — | EP | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |