Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.63 |
| ▸ | IDH1 | O75874 | 5/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97723 | 0.84 | POLB (0.50) | CCR2POLBPIK3CBRORCBRD4 | |
| SCHEMBL8125111 | 0.84 | GAA (0.54) | CCR2POLBPIK3CBRORCBRD4 | |
| SCHEMBL17609451 | 0.83 | PTK2B (0.55) | CCR2POLBPIK3CBRORCBRD4 | |
| SCHEMBL8113005 | 0.82 | POLB (0.51) | CCR2POLBPIK3CBRORCBRD4 | |
| SCHEMBL3771893 | 0.81 | CCR2 (0.60) | CCR2 | |
| SCHEMBL15836458 | 0.80 | PIK3CB (0.47) | CCR2POLBPIK3CBRORCBRD4 | |
| SCHEMBL7571634 | 0.80 | SLC22A12 (0.53) | CCR2POLBPIK3CBRORCBRD4 | |
| SCHEMBL15713386 | 0.80 | PTK2B (0.59) | POLBTDP1RORC | |
| SCHEMBL1638685 | 0.78 | CCR2 (0.56) | CCR2POLB | |
| SCHEMBL22095987 | 0.78 | SMN1; SMN2 (0.78) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |