Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 5/20 | 0.48 |
| ▸ | THRB | P10828 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512413 | 0.82 | THRA (0.61) | GAAALDH1A1SMN1; SMN2THRATHRB | |
| SCHEMBL7568596 | 0.79 | GAA (0.50) | GAAALDH1A1SMN1; SMN2THRATHRB | |
| SCHEMBL1642319 | 0.76 | THRA (0.59) | THRATHRB | |
| SCHEMBL6738420 | 0.76 | THRA (0.44) | GAAALDH1A1SMN1; SMN2THRATHRB | |
| SCHEMBL7574842 | 0.75 | GAA (0.46) | GAAALDH1A1SMN1; SMN2THRBL3MBTL1 | |
| SCHEMBL7517348 | 0.75 | THRA (0.60) | GAAALDH1A1THRATHRBL3MBTL1 | |
| SCHEMBL6735849 | 0.75 | THRA (0.50) | GAASMN1; SMN2THRATHRBKMT2A | |
| SCHEMBL6735850 | 0.75 | THRA (0.50) | GAASMN1; SMN2THRATHRBKMT2A | |
| SCHEMBL7516945 | 0.74 | THRA (0.59) | GAAALDH1A1SMN1; SMN2THRATHRB | |
| SCHEMBL1642407 | 0.73 | THRA (0.58) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002090344-A1 | AMIDO-DIPHENYL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-14 | — | — | WO | disclosed |