Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 4/20 | 0.40 |
| ▸ | THRA | P10827 | 3/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961754 | 0.88 | GAA (0.41) | GAAPOLBGFERL3MBTL1MEN1 | |
| SCHEMBL7574842 | 0.83 | GAA (0.46) | GAAPOLBGFERL3MBTL1MEN1 | |
| SCHEMBL7512413 | 0.82 | THRA (0.61) | GAAPOLBGFERL3MBTL1ALDH1A1 | |
| SCHEMBL6861848 | 0.81 | THRB (0.42) | GAAPOLBALDH1A1PKMTHRB | |
| SCHEMBL7572533 | 0.79 | GAA (0.48) | GAAPOLBGFERL3MBTL1MEN1 | |
| SCHEMBL7592718 | 0.78 | SOS1 (0.47) | GAAPOLBGFERL3MBTL1MEN1 | |
| SCHEMBL3004495 | 0.76 | HTT (0.49) | GAAPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL6861552 | 0.75 | THRB (0.40) | GAAL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL7042666 | 0.75 | THRB (0.55) | THRBTHRA | |
| SCHEMBL6741329 | 0.75 | THRB (0.38) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002090344-A1 | AMIDO-DIPHENYL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-14 | — | — | WO | disclosed |