SCHEMBL7572629

SCHEMBL7572629

Fc1cc(C#CC/N=C/c2ccccc2)cs1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.31
LMNA P02545 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7572630 1.00 CA2 (0.31) CA2LMNAL3MBTL1SMN1; SMN2
SCHEMBL7574047 0.84 CA2 (0.32) CA2LMNAL3MBTL1SMN1; SMN2
SCHEMBL7574040 0.84 CA2 (0.32) CA2LMNAL3MBTL1SMN1; SMN2
SCHEMBL7573202 0.83 ALDH1A1 (0.32) CA2LMNAL3MBTL1SMN1; SMN2
SCHEMBL7579473 0.83 CA2 (0.31) CA2LMNAL3MBTL1SMN1; SMN2
SCHEMBL7579481 0.83 CA2 (0.31) CA2LMNAL3MBTL1SMN1; SMN2
SCHEMBL7573201 0.83 ALDH1A1 (0.32) CA2LMNAL3MBTL1SMN1; SMN2
SCHEMBL7571246 0.78 CYP1A2 (0.45) CA2LMNAL3MBTL1
SCHEMBL7571250 0.78 CYP1A2 (0.45) CA2LMNAL3MBTL1
SCHEMBL7580085 0.75 CYP2A6 (0.36) CA2LMNAL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0810199-B1 Method for producing propargylamine compounds SUMITOMO CHEMICAL CO (JP) 2002-09-25 EP disclosed
US-5756769-A Method for producing propargylamine compounds SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1998-05-26 US disclosed
EP-0810199-A1 Method for producing propargylamine compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-03 EP disclosed