Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 3/20 | 0.44 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 6/20 | 0.53 |
| ▸ | DRD2 | P14416 | 8/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 6/20 | 0.42 |
| ▸ | HTR7 | P34969 | 6/20 | 0.42 |
| ▸ | HTR6 | P50406 | 6/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7214633 | 0.83 | HTR1D (0.52) | HTR1DDRD2SLC6A4ADRA1DHTR1B | |
| SCHEMBL6802859 | 0.83 | HTR1D (0.49) | HTR1DDRD2SLC6A4HTR1AHTR7 | |
| SCHEMBL7219879 | 0.81 | HTR1D (0.54) | HTR1DDRD2SLC6A4ADRA1DHTR1B | |
| Oxalic Acid SCHEMBL7214504 | 0.81 | HTR1D (0.54) | HTR1DDRD2SLC6A4HTR1AHTR7 | |
| SCHEMBL7213620 | 0.81 | HTR1D (0.56) | HTR1DDRD2SLC6A4HTR1AHTR7 | |
| Oxalic Acid SCHEMBL7220017 | 0.79 | HTR1D (0.49) | HTR1DDRD2SLC6A4HTR1AHTR7 | |
| Oxalic Acid SCHEMBL7219944 | 0.79 | HTR1D (0.49) | HTR1DDRD2SLC6A4HTR1AHTR7 | |
| SCHEMBL7220152 | 0.77 | OPRM1 (0.51) | HTR1DDRD2SLC6A4HTR1AHTR7 | |
| SCHEMBL7213738 | 0.77 | HTR1D (0.51) | HTR1DDRD2SLC6A4HTR1AHTR7 | |
| SCHEMBL6795818 | 0.77 | OPRM1 (0.56) | DRD2SLC6A4HTR1AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946542-A1 | INDANE OR DIHYDROINDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028293-A1 | INDANE OR DIHYDROINDOLE DERIVATIVES | H.LUNDBECK A/S (DK) | 1998-07-02 | — | — | WO | disclosed |