Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708728 | 1.00 | OPRM1 (0.43) | OPRM1OPRD1OPRK1OPRL1MET | |
| SCHEMBL541617 | 1.00 | OPRM1 (0.43) | OPRM1OPRD1OPRK1OPRL1MET | |
| SCHEMBL5081429 | 1.00 | OPRM1 (0.43) | OPRM1OPRD1OPRK1OPRL1MET | |
| SCHEMBL7359458 | 1.00 | OPRM1 (0.43) | OPRM1OPRD1OPRK1OPRL1MET | |
| SCHEMBL4964887 | 1.00 | OPRM1 (0.43) | OPRM1OPRD1OPRK1OPRL1MET | |
| SCHEMBL3711846 | 1.00 | OPRM1 (0.43) | OPRM1OPRD1OPRK1OPRL1MET | |
| SCHEMBL30742696 | 0.97 | OPRM1 (0.42) | OPRM1OPRD1OPRK1OPRL1MET | |
| SCHEMBL4613762 | 0.97 | TSHR (0.40) | OPRM1OPRD1OPRK1OPRL1MET | |
| SCHEMBL9891 | 0.97 | TSHR (0.40) | OPRM1OPRD1OPRK1OPRL1MET | |
| SCHEMBL641967 | 0.97 | TSHR (0.40) | OPRM1OPRD1OPRK1OPRL1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676201-B1 | Use of a riminophenazine for treating MDR resistance | UNIV PRETORIA (ZA) | 2002-09-11 | — | — | EP | disclosed |
| EP-0676201-A2 | Use of a riminophenazine for treating MDR resistance | ADCOCK INGRAM LIMITED (ZA) | 1995-10-11 | — | — | EP | disclosed |