Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | RXRG | P48443 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1363057 | 0.88 | MAPT (0.39) | CYP3A4CYP2D6LMNAMAPTKDM4E | |
| SCHEMBL7507030 | 0.85 | PPARD (0.41) | SIRT2LMNAMAPTKDM4EPPARD | |
| SCHEMBL1361779 | 0.84 | GCGR (0.34) | RXRARXRBRXRGLMNAMAPT | |
| SCHEMBL203742 | 0.84 | TP53 (0.41) | LMNAMAPTMEN1KMT2A | |
| SCHEMBL962882 | 0.83 | MAPT (0.36) | CYP3A4LMNAMAPTMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL1362475 | 0.83 | TP53 (0.41) | LMNAMAPTMEN1KMT2A | |
| SCHEMBL1361418 | 0.83 | MAPT (0.42) | CYP3A4CYP2D6LMNAMAPTMEN1 | |
| SCHEMBL1361746 | 0.83 | GCGR (0.38) | CYP3A4CYP2D6MAPTMEN1CYP1A2 | |
| SCHEMBL1361106 | 0.83 | TUBB4A (0.35) | KCNH2LMNAMAPTMEN1KMT2A | |
| SCHEMBL1362894 | 0.83 | RXRA (0.41) | RXRARXRBRXRGFFAR4PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206472-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AS NEUROTROPHIN PRODUCTION/SECRETION PROMOTING AGENT | Takeda Chemical Industries, Ltd. (JP) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001014372-A2 | OXAZOLE AND THIAZOLE DERIVATIVES AS NEUROTROPHIN PRODUCTION/SECRETION PROMOTING AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-01 | — | — | WO | disclosed |