Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573318 | 1.00 | LMNA (0.35) | LMNAL3MBTL1CA2KMT2AMEN1 | |
| SCHEMBL7572626 | 0.87 | LMNA (0.38) | LMNAL3MBTL1CA2KMT2AMEN1 | |
| SCHEMBL7572622 | 0.87 | LMNA (0.38) | LMNAL3MBTL1CA2KMT2AMEN1 | |
| SCHEMBL7574912 | 0.81 | LMNA (0.41) | LMNAL3MBTL1CA2KMT2AMEN1 | |
| SCHEMBL7574914 | 0.81 | LMNA (0.41) | LMNAL3MBTL1CA2KMT2AMEN1 | |
| SCHEMBL7571324 | 0.81 | LMNA (0.35) | LMNAL3MBTL1CA2KMT2AMEN1 | |
| SCHEMBL7571320 | 0.81 | LMNA (0.35) | LMNAL3MBTL1CA2KMT2AMEN1 | |
| SCHEMBL7573421 | 0.79 | GRIN1 (0.36) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7573424 | 0.79 | GRIN1 (0.36) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7573504 | 0.79 | G6PD (0.41) | LMNAKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |