Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2488724 | 0.85 | KMT2A (0.57) | ALDH1A1NPSR1LMNAMAPTMEN1 | |
| SCHEMBL13240813 | 0.85 | KMT2A (0.57) | ALDH1A1NPSR1LMNAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL2485666 | 0.84 | KMT2A (0.56) | ALDH1A1NPSR1LMNAMAPTMEN1 | |
| SCHEMBL13240794 | 0.83 | TDP1 (0.51) | ALDH1A1LMNAMAPTTDP1MEN1 | |
| SCHEMBL2488262 | 0.83 | TDP1 (0.51) | ALDH1A1LMNAMAPTTDP1MEN1 | |
| Hydrochloric Acid SCHEMBL2485674 | 0.81 | TDP1 (0.50) | ALDH1A1LMNAMAPTTDP1MEN1 | |
| SCHEMBL7577574 | 0.81 | MEN1 (0.48) | ALDH1A1NPSR1L3MBTL1MEN1KMT2A | |
| SCHEMBL7575575 | 0.80 | KCNMA1 (0.54) | NPSR1LMNAMAPTCRHBPCRHR2 | |
| SCHEMBL7574996 | 0.80 | MEN1 (0.66) | ALDH1A1NPSR1L3MBTL1LMNAMAPT | |
| SCHEMBL7598789 | 0.80 | ALDH1A1 (0.62) | ALDH1A1NPSR1LMNAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |