SCHEMBL7573378

SCHEMBL7573378

C=C(CN(C)CC)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.35
EGFR P00533 2/20 0.34
TET3 O43151 1/20 0.33
TET1 Q8NFU7 1/20 0.33
CYP2C19 P33261 1/20 0.33
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
GRM1 Q13255 1/20 0.32
GRM2 Q14416 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KDM5A P29375 1/20 0.32
KDM4C Q9H3R0 1/20 0.32
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1642046 0.81 TET2 (0.35) TET2EGFRTET3TET1GRIK1
SCHEMBL676069 0.78 ALDH1A1 (0.37) TET2EGFRTET3TET1GRIK1
SCHEMBL7783889 0.77 FFAR3 (0.39) TET2TET3TET1GRIK1GRIK2
SCHEMBL2151088 0.77 KDM5A (0.41) TET2TET3TET1GRIK1GRIK2
SCHEMBL164434 0.77
Hydrochloric Acid SCHEMBL7060187 0.76 FFAR3 (0.37) TET2EGFRTET3TET1KDM5A
Methacrylic Acid SCHEMBL3856792 0.75 TDP1 (0.35) CYP2C19KDM5AKDM4C
Hydrochloric Acid SCHEMBL20699298 0.75 EGFR (0.53) TET2EGFRTET3TET1CYP2C19
SCHEMBL2282136 0.74 EGFR (0.46) TET2EGFRTET3TET1GRIK1
SCHEMBL31271211 0.74 TET2 (0.37) TET2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0272562-B1 Basic adhesive polymeric mass transmitting the active ingredient, method for making it and its use LOHMANN THERAPIE SYST LTS (DE) 1994-03-09 EP claimed
EP-2354134-A1 2H-CHROMENE COMPOUND AND DERIVATIVE THEREOF Astellas Pharma Inc. (JP) 2011-08-10 EP disclosed
EP-0878320-B1 Ink acceptor and recording method using the same GEN CO LTD (JP) 2002-09-11 EP disclosed
US-6132039-A Ink acceptor and recording method using the same GENERAL COMPANY LIMITED (JP) 2000-10-17 US disclosed
EP-0878320-A1 Ink acceptor and recording method using the same General Company Limited (JP) 1998-11-18 EP disclosed
EP-0272562-B1 Basic adhesive polymeric mass transmitting the active ingredient, method for making it and its use LOHMANN THERAPIE SYST LTS (DE) 1994-03-09 EP disclosed
EP-0269981-A1 3-[alpha-(3,5-di-t-butyl-4-hydroxyphenyl)-alkanoyl]pyrroles, their de-oxy analogs, and therapeutic uses thereof SYNTEX (U.S.A.) INC. (US) 1988-06-08 EP disclosed