Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571863 | 0.83 | LMNA (0.31) | TSHRHTTSMN1; SMN2 | |
| SCHEMBL7573562 | 0.83 | KMT2A (0.32) | KMT2A | |
| SCHEMBL7581864 | 0.81 | — | — | |
| SCHEMBL7575152 | 0.73 | CHRM2 (0.39) | — | |
| SCHEMBL6200902 | 0.72 | LMNA (0.41) | PTGDR2MEN1KMT2A | |
| SCHEMBL7581246 | 0.69 | — | — | |
| SCHEMBL4387264 | 0.69 | PTGDR2 (0.39) | PTGDR2ADORA3DRD1TSHR | |
| SCHEMBL3452817 | 0.68 | CA12 (0.51) | MEN1KMT2AHTT | |
| SCHEMBL31046612 | 0.68 | CYP2D6 (0.44) | PTGDR2 | |
| SCHEMBL7581858 | 0.68 | CYP2D6 (0.44) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |