Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1793714 | 0.81 | TAAR1 (0.51) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL2352950 | 0.81 | PARP1 (0.38) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL1794401 | 0.73 | TAAR1 (0.47) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL14856734 | 0.71 | TAAR1 (0.46) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL2791377 | 0.71 | TAAR1 (0.42) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL1810955 | 0.71 | TAAR1 (0.46) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL14856666 | 0.71 | TAAR1 (0.58) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL7573772 | 0.70 | TBXAS1 (0.46) | TBXAS1 | |
| SCHEMBL10947863 | 0.68 | TP53 (0.44) | TAAR1HTR1AADORA3ADORA2AADORA2B | |
| SCHEMBL1812653 | 0.67 | TAAR1 (0.42) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083146-A1 | MULTIPLE DOSE AROMATASE INHIBITOR FOR TREATING INFERTILITY | ARES TRADING S.A. (CH) | 2002-10-24 | — | — | WO | disclosed |