Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1793714 | 0.83 | TAAR1 (0.51) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL1811127 | 0.74 | TAAR1 (0.44) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL14856666 | 0.73 | TAAR1 (0.58) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL1810955 | 0.73 | TAAR1 (0.46) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL1807964 | 0.73 | TAAR1 (0.46) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL1794401 | 0.72 | TAAR1 (0.47) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL14856734 | 0.69 | TAAR1 (0.46) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL1810035 | 0.68 | TAAR1 (0.39) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL7573780 | 0.67 | TAAR1 (0.43) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B | |
| SCHEMBL7019374 | 0.67 | TAAR1 (0.57) | TAAR1HTR1ACSNK1A1TYRO3DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110142856-A1 | COMPOUND CONTAINING BASIC GROUP AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-06-16 | — | — | US | disclosed |
| US-7951816-B2 | Compound containing basic group and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110142856-A1 | COMPOUND CONTAINING BASIC GROUP AND USE THEREOF | CXCR4, CCR5, CXCL12 | TAAR1 903/4885HTR1A 2622/4885CSNK1A1 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.