Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 10/20 | 0.62 |
| ▸ | HTT | P42858 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | RECQL | P46063 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15821860 | 0.81 | MEN1 (0.74) | KMT2ALMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL19334483 | 0.78 | MAPT (0.51) | KMT2ATSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL1653127 | 0.78 | MAPT (0.51) | KMT2ATSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL7573029 | 0.77 | PTGES2 (0.74) | KMT2ALMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL26188511 | 0.77 | LMNA (0.81) | KMT2ATSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL14574872 | 0.76 | TSHR (0.72) | KMT2ATSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL2634116 | 0.76 | TSHR (0.84) | KMT2ATSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL7572290 | 0.76 | LMNA (0.72) | KMT2ATSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL14498263 | 0.76 | KCNA5 (0.69) | KMT2ALMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL5072752 | 0.76 | KCNA5 (0.69) | KMT2ALMNAHTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |