SCHEMBL7573906

SCHEMBL7573906

CCCCOc1c(C#N)c(C#N)c(OCCCC)c(-c2cccc(OC)c2)c1-c1cccc(OC)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 5/20 0.44
ADORA2A P29274 4/20 0.44
ADORA2B P29275 2/20 0.44
HPGD P15428 2/20 0.44
HTT P42858 2/20 0.44
TP53 P04637 1/20 0.44
GRIA2 P42262 1/20 0.44
GRIA4 P48058 1/20 0.44
MAPK1 P28482 2/20 0.43
FNTA P49354 1/20 0.43
FNTB P49356 1/20 0.43
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
BTK Q06187 1/20 0.42
ADORA3 P0DMS8 1/20 0.41
MAPT P10636 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
SQOR Q9Y6N5 1/20 0.41
GCGR P47871 1/20 0.41
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7573733 0.84 GRM2 (0.41) ADORA1ADORA2AADORA2BHPGDHTT
SCHEMBL7573754 0.82 MAPT (0.45) ADORA1ADORA2AHPGDHTTTP53
SCHEMBL7572014 0.73 CYP2D6 (0.53) HPGDHTTTP53MAPK1MAPT
SCHEMBL7580611 0.73 MAPT (0.44) ADORA1HPGDHTTMAPTRXFP1
SCHEMBL7582390 0.72 GCGR (0.40) ADORA2AADORA3MAPTGCGRCYP1A2
SCHEMBL16673312 0.72 GAA (0.43) HPGDMAPTCYP1A2CYP2C9CYP2C19
SCHEMBL29152130 0.72 ADORA1 (0.53) ADORA1ADORA2AADORA2BHPGDHTT
1-Butyloxy-3-Methoxybenzene SCHEMBL1071738 0.71 MAPK1 (0.61) MAPK1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL8402204 0.71 BTK (0.52) ADORA1ADORA2AADORA2BHPGDHTT
SCHEMBL12879202 0.71 CYP11B1 (0.57) HPGDHTTCYP11B1CYP11B2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002096913-A1 SUBSTITUTED DI(HYDROXY/ALKOXY)SILICON PHTHALOCYANINES AND THEIR USES GENTIAN AS (NO) 2002-12-05 WO disclosed