Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573754 | 0.84 | MAPT (0.45) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL7572253 | 0.81 | CYP3A4 (0.46) | CYP2D6CYP3A4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7573906 | 0.73 | ADORA1 (0.44) | KDM4EALDH1A1MAPTMAPK1HPGD | |
| SCHEMBL1524981 | 0.72 | LTA4H (0.42) | KDM4EALDH1A1MAPTLMNATSHR | |
| SCHEMBL30509797 | 0.72 | LTA4H (0.42) | KDM4EALDH1A1MAPTLMNATSHR | |
| SCHEMBL7573040 | 0.72 | THRA (0.39) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL5792998 | 0.71 | ELANE (0.41) | CYP2D6CYP3A4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL12681345 | 0.70 | MAPT (0.48) | CYP2D6CYP3A4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL6440940 | 0.70 | HSD17B10 (0.62) | KDM4EALDH1A1HSD17B10MAPTLMNA | |
| SCHEMBL14129958 | 0.70 | CYP2D6 (1.00) | CYP2D6CYP3A4KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002096913-A1 | SUBSTITUTED DI(HYDROXY/ALKOXY)SILICON PHTHALOCYANINES AND THEIR USES | GENTIAN AS (NO) | 2002-12-05 | — | — | WO | disclosed |