Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7580611 | 0.88 | MAPT (0.44) | HPGDHTTADORA1NPSR1KDM4E | |
| SCHEMBL7573073 | 0.85 | KDM4E (0.39) | HPGDHTTTP53KDM4ESQOR | |
| SCHEMBL7573906 | 0.84 | ADORA1 (0.44) | CYP11B1CYP11B2BTKHPGDHTT | |
| Dimethylamine SCHEMBL7572333 | 0.82 | KDM4E (0.39) | HPGDHTTKDM4ESQORMAPK1 | |
| SCHEMBL7715410 | 0.79 | L3MBTL1 (0.39) | FPR2HPGDHTTTP53NPSR1 | |
| SCHEMBL7572253 | 0.78 | CYP3A4 (0.46) | CYP11B1CYP11B2HPGDKDM4ESQOR | |
| SCHEMBL7573743 | 0.78 | MAPT (0.41) | HPGDHTTADORA2AADORA1TP53 | |
| SCHEMBL7575694 | 0.77 | CNR2 (0.39) | GRM2HPGDCNR1CNR2PDCD1 | |
| SCHEMBL7572329 | 0.76 | PIM1 (0.41) | GRM2HPGDADORA1KDM4ECNR1 | |
| SCHEMBL7576174 | 0.76 | PDE3A (0.46) | HPGDADORA2AADORA1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002096913-A1 | SUBSTITUTED DI(HYDROXY/ALKOXY)SILICON PHTHALOCYANINES AND THEIR USES | GENTIAN AS (NO) | 2002-12-05 | — | — | WO | disclosed |