Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.74 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.74 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.74 |
| ▸ | CDK2 | P24941 | 2/20 | 0.74 |
| ▸ | CDK7 | P50613 | 2/20 | 0.74 |
| ▸ | CCNH | P51946 | 2/20 | 0.74 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.74 |
| ▸ | CCND1 | P24385 | 1/20 | 0.74 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | IDH1 | O75874 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SGK1 | O00141 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573900 | 0.90 | CDK1 (0.72) | CDK1CCNB1CCNA2CDK2CDK7 | |
| SCHEMBL31060131 | 0.85 | CDK1 (1.00) | CDK1CCNB1CCNA2CDK2CDK7 | |
| SCHEMBL7571716 | 0.81 | CDK1 (0.77) | CDK1CCNB1CCNA2CDK2CDK7 | |
| SCHEMBL7592196 | 0.81 | CDK1 (0.63) | CDK1CCNB1CCNA2CDK2CDK7 | |
| SCHEMBL7578134 | 0.79 | LMNA (0.71) | TDP1PKMALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7579927 | 0.78 | CDK1 (0.72) | CDK1CCNB1CCNA2CDK2CDK7 | |
| SCHEMBL7569616 | 0.75 | CDK1 (0.68) | CDK1CCNB1CCNA2CDK2CDK7 | |
| SCHEMBL7594749 | 0.75 | CDK1 (0.58) | CDK1CCNB1CCNA2CDK2CDK7 | |
| SCHEMBL16325537 | 0.75 | CDK1 (0.65) | CDK1CCNB1CCNA2CDK2CDK7 | |
| SCHEMBL9996819 | 0.74 | PFKFB3 (1.00) | CDK1CCNB1CCNA2CDK2CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |