SCHEMBL7574023

SCHEMBL7574023

Cc1cc(C(C)(C)C)cc(C(C)(C)C)c1C[PH](O)(O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 5/20 0.44
HTR1B P28222 3/20 0.44
POLB P06746 3/20 0.36
TSHR P16473 3/20 0.35
HTR1A P08908 2/20 0.35
ADRA2A P08913 2/20 0.35
ADRA2B P18089 2/20 0.35
ADRA2C P18825 2/20 0.35
TP53 P04637 2/20 0.35
LMNA P02545 2/20 0.35
CHRM2 P08172 1/20 0.35
CYP2D6 P10635 1/20 0.35
CHRM1 P11229 1/20 0.35
DRD2 P14416 1/20 0.35
CHRM3 P20309 1/20 0.35
ADRA1D P25100 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
MAPK1 P28482 1/20 0.35
ADRA1A P35348 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6668865 0.79 HTR1D (0.48) HTR1DHTR1BPOLBTSHRHTR1A
SCHEMBL4412838 0.78 HTR1D (0.52) HTR1DHTR1BPOLBTSHRHTR1A
SCHEMBL26876706 0.76 HTR1D (0.55) HTR1DHTR1BPOLBTSHRHTR1A
SCHEMBL15064207 0.75 HTR1D (0.48) HTR1DHTR1BPOLBTSHRHTR1A
SCHEMBL29912683 0.73 CYP2C19 (0.53) POLBTSHRTP53LMNACYP2D6
SCHEMBL28891370 0.72 POLB (0.41) HTR1DHTR1BPOLBTSHRTP53
SCHEMBL5915880 0.71 GABRA1 (0.42) HTR1DHTR1BTSHRGABRA1GABRB2
SCHEMBL27878425 0.70 CYP1A2 (0.41) HTR1DHTR1BTSHRADRA2AADRA2B
SCHEMBL39016 0.70 CYP2C9 (0.37) HTR1DHTR1BPOLBTSHRTP53
SCHEMBL7574017 0.70 HTR1D (0.41) HTR1DHTR1BPOLBTSHRHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002042368-A2 METHOD FOR STABILIZING POLYOLEFINS BASF AKTIENGESELLSCHAFT (DE) 2002-05-30 WO disclosed
EP-1181330-A1 MIXTURES CONTAINING STABILISERS AND IMINOPHOSPHORANES BASF AKTIENGESELLSCHAFT (DE) 2002-02-27 EP disclosed
WO-2000066661-A1 MIXTURES CONTAINING STABILISERS AND IMINOPHOSPHORANES BASF AKTIENGESELLSCHAFT (DE) 2000-11-09 WO disclosed