Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 7/20 | 0.52 |
| ▸ | HTR1B | P28222 | 5/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26876706 | 0.84 | HTR1D (0.55) | HTR1DHTR1BHTR1AADRA2AADRA2B | |
| SCHEMBL15064207 | 0.83 | HTR1D (0.48) | HTR1DHTR1BHTR1AADRA2AADRA2B | |
| SCHEMBL6668865 | 0.83 | HTR1D (0.48) | HTR1DHTR1BHTR1AADRA2AADRA2B | |
| SCHEMBL11087884 | 0.80 | THRA (0.44) | HTR1DHTR1BTSHRLMNACYP3A4 | |
| SCHEMBL10891430 | 0.78 | CYP2C9 (0.46) | HTR1DHTR1BHTR1AADRA2AADRA2B | |
| SCHEMBL6299373 | 0.78 | ALDH1A1 (0.44) | HTR1DHTR1BCYP2D6TSHRLMNA | |
| SCHEMBL7574023 | 0.78 | HTR1D (0.44) | HTR1DHTR1BHTR1AADRA2AADRA2B | |
| SCHEMBL11087876 | 0.78 | HSPA5 (0.44) | HTR1DHTR1BCYP2D6TSHRCYP3A4 | |
| SCHEMBL26874266 | 0.77 | HTR1D (0.43) | HTR1DHTR1BHTR1AADRA2AADRA2B | |
| SCHEMBL13672404 | 0.76 | HTR1D (0.50) | HTR1DHTR1BHTR1AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3168252-B1 | POLYKETONE MOULDING MATERIALS WITH IMPROVED PROPERTIES, MOULDED PARTS PRODUCED THEREFROM AND METHOD FOR ITS MANUFACTURE | EMS PATENT AG (CH) | 2019-01-09 | — | — | EP | claimed |
| EP-3168253-B1 | FLAME RETARDANT ALIPHATIC POLYKETONE MASSES, MOULDS OBTAINED FROM THESE AND METHOD FOR PREPARING THE SAME | EMS PATENT AG (CH) | 2018-04-11 | — | — | EP | claimed |
| EP-1379584-B1 | FLAME RETARDANT COMPOSITIONS | CIBA SC HOLDING AG (CH) | 2005-08-24 | — | — | EP | claimed |
| CN-113166467-A | Polyethylene or polypropylene articles | 巴斯夫欧洲公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-2502638-B1 | COMPOSITION FOR HARD TISSUE REPAIR | MITSUI CHEMICALS INC (JP) | 2018-02-21 | — | — | EP | disclosed |
| EP-2640777-B1 | STABILIZER COMPOSITION FOR POLYMERS | BASF SE (DE) | 2015-01-07 | — | — | EP | disclosed |
| EP-2502638-A1 | COMPOSITION FOR HARD TISSUE REPAIR | Mitsui Chemicals, Inc. (JP) | 2012-09-26 | — | — | EP | disclosed |
| EP-1513893-B1 | FLAME RETARDANT POLYMER COMPOSITIONS CONTAINING HYDROXYLAMINE ESTERS | CIBA HOLDING INC (CH) | 2009-01-07 | — | — | EP | disclosed |
| EP-1507824-B1 | STABILIZED ARTICLES | CIBA SC HOLDING AG (CH) | 2008-03-12 | — | — | EP | disclosed |
| EP-1263833-A1 | ROMP WITH OLIGOMERIC UV-ABSORBERS | Ciba SC Holding AG (CH) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001062821-A1 | ROMP WITH OLIGOMERIC UV-ABSORBERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-08-30 | — | — | WO | disclosed |