SCHEMBL7574131

SCHEMBL7574131

O=C1Nc2ccccc2C(=O)C1S(=O)(=O)Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
PDGFRA P16234 1/20 0.40
FER P16591 1/20 0.40
LTK P29376 1/20 0.40
CDK8 P49336 1/20 0.40
ACVR1 Q04771 1/20 0.40
LRRK2 Q5S007 1/20 0.40
DYRK1B Q9Y463 1/20 0.40
S100A4 P26447 1/20 0.39
BRPF1 P55201 1/20 0.37
CREBBP Q92793 1/20 0.37
MAPT P10636 3/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
ALDH1A1 P00352 3/20 0.37
LMNA P02545 3/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4163696 0.79 IDO1 (0.45) BRPF1CREBBPMAPTALDH1A1TDP1
SCHEMBL1074137 0.71 LRRK2 (0.45) MAOAMAOBPDGFRAFERLTK
SCHEMBL11451121 0.71 CREBBP (0.50) MAOAMAOBPDGFRAFERLTK
SCHEMBL28338332 0.71 LRRK2 (0.45) MAOAMAOBPDGFRAFERLTK
SCHEMBL30122758 0.71 MAOA (0.45) MAOAMAOBPDGFRAFERLTK
SCHEMBL9393278 0.69 MEN1 (0.59) MAOAMAOBPDGFRAFERLTK
SCHEMBL13685637 0.68 MAPT (0.59) MAOAMAOBPDGFRAFERLTK
SCHEMBL6684295 0.67 MAPT (0.46) MAOAMAOBPDGFRAFERLTK
SCHEMBL14375245 0.67 PIM1 (0.60) MAOAMAOBPDGFRAFERLTK
SCHEMBL30556308 0.67 MAOA (0.41) MAOAMAOBPDGFRAFERLTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053508-B1 A PROCESS FOR MAKING A PHOTOACTIVE COMPOUND AND PHOTORESIST THEREFROM CLARIANT FINANCE BVI LTD (VG) 2002-08-28 EP claimed
EP-1053508-A1 A PROCESS FOR MAKING A PHOTOACTIVE COMPOUND AND PHOTORESIST THEREFROM Clariant International Ltd. (CH) 2000-11-22 EP claimed
US-5936071-A Process for making a photoactive compound and photoresist therefrom CLARIANT FINANCE (BVI) LIMITED (VG) 1999-08-10 US claimed
WO-1999039245-A1 A PROCESS FOR MAKING A PHOTOACTIVE COMPOUND AND PHOTORESIST THEREFROM CLARIANT INTERNATIONAL LTD. (CH) 1999-08-05 WO claimed