Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 0.77 |
| ▸ | KDR | P35968 | 15/20 | 0.66 |
| ▸ | RET | P07949 | 2/20 | 0.60 |
| ▸ | KIF5B | P33176 | 2/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.58 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 3/20 | 0.56 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456204 | 0.83 | FLT1 (0.81) | KDREGFRFLT1FGFR1FLT4 | |
| SCHEMBL7573786 | 0.82 | SRC (0.80) | SRCKDRRETKIF5BERBB2 | |
| SCHEMBL3193735 | 0.81 | KDR (0.77) | SRCKDREPHA2EGFRFLT1 | |
| SCHEMBL3203336 | 0.81 | KDR (0.84) | SRCKDRERBB2EGFRFLT1 | |
| SCHEMBL7454646 | 0.80 | FLT1 (0.78) | KDREGFRFLT1FGFR1FLT4 | |
| SCHEMBL3193440 | 0.80 | SRC (0.92) | SRCKDREPHA2EGFRFLT1 | |
| Hydrochloric Acid SCHEMBL7573245 | 0.80 | KDR (0.83) | SRCKDRERBB2EGFRFLT1 | |
| SCHEMBL7580350 | 0.80 | SRC (0.76) | SRCKDRRETKIF5BERBB2 | |
| SCHEMBL7580342 | 0.80 | SRC (0.76) | SRCKDRRETKIF5BERBB2 | |
| SCHEMBL7572205 | 0.80 | SRC (0.76) | SRCKDRRETKIF5BERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002092577-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2002-11-21 | — | — | WO | disclosed |