Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19443144 | 0.86 | MCL1 (0.46) | GAASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL3152318 | 0.81 | CA12 (0.62) | GAASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL7572980 | 0.81 | GAA (0.49) | GAASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL11775724 | 0.80 | MCL1 (0.59) | GAASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL29800681 | 0.80 | MCL1 (0.59) | GAASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL19434336 | 0.80 | MCL1 (0.46) | GAASMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL34468742 | 0.80 | CA2 (0.40) | GAAMAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL27458187 | 0.80 | CFTR (0.39) | GAASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL3139456 | 0.79 | KDM4E (0.50) | GAASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL6492188 | 0.79 | ALDH1A1 (0.62) | GAASMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101287729-A | GPCR agonists | PROSIDION LTD (GB) | 2008-10-15 | — | — | CN | disclosed |
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| US-5374606-A | Pre- and postemergence | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |