Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10397908 | 0.79 | HSD17B2 (0.39) | ALDH1A1SMN1; SMN2HPGDCES2KDM4E | |
| SCHEMBL7584988 | 0.79 | MAOB (0.38) | ALDH1A1NCEH1HPGDHTTCES2 | |
| SCHEMBL7584139 | 0.78 | HPGD (0.40) | ALDH1A1SMN1; SMN2HPGDHTTKDM4E | |
| SCHEMBL4147742 | 0.78 | HTT (0.38) | ALDH1A1SMN1; SMN2HPGDHTTPOLB | |
| SCHEMBL4023724 | 0.76 | KDM4E (0.39) | ALDH1A1SMN1; SMN2HPGDCES2GALR3 | |
| SCHEMBL10388490 | 0.76 | PARP1 (0.45) | SMN1; SMN2HPGDCES2GALR3KDM4E | |
| SCHEMBL28294101 | 0.76 | NR4A2 (0.41) | ALDH1A1SMN1; SMN2HPGDRECQLHTT | |
| SCHEMBL28079948 | 0.74 | GAA (0.41) | ALDH1A1LMNASMN1; SMN2HPGDKDM4E | |
| SCHEMBL3461270 | 0.74 | CREBBP (0.41) | LMNASMN1; SMN2HPGDHTT | |
| SCHEMBL4151206 | 0.72 | ALDH1A1 (0.43) | ALDH1A1LMNANCEH1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882730-B1 | PHOSPHONIC ACID DIESTER DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| EP-0718432-B1 | Curable coating compositions | DOW CORNING LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| US-6387451-B1 | SILICONE RESIN, ADHESION PROMOTING ADDITIVE, INHIBITOR; CURING BY HYDROSILATION REACTION | DOW CORNING LIMITED (GB) | 2002-05-14 | — | — | US | disclosed |
| US-5985858-A | TREATING AND PREVENTING HYPERLIPIDEMIA, DIABETES AND CATARACT, OR AS AN ANTITUMOR AGENT | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0882730-A1 | PHOSPHONIC ACID DIESTER DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-12-09 | — | — | EP | disclosed |
| EP-0718432-A1 | Curable coating compositions | DOW CORNING LIMITED (GB) | 1996-06-26 | — | — | EP | disclosed |