Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.48 |
| ▸ | YAP1 | P46937 | 1/20 | 0.48 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.48 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353910 | 0.88 | KCNH2 (0.58) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL6045428 | 0.85 | TTR (0.52) | CAPN1KDM4EALDH1A1HPGDMAOA | |
| SCHEMBL14827124 | 0.85 | NPC1 (0.54) | CAPN1KDM4EALDH1A1HPGDMAOA | |
| SCHEMBL29587413 | 0.85 | TTR (0.52) | CAPN1KDM4EALDH1A1HPGDMAOA | |
| SCHEMBL30224972 | 0.81 | CYP3A4 (0.54) | KDM4EALDH1A1HPGDMAOASMN1; SMN2 | |
| SCHEMBL9782978 | 0.80 | MAPT (0.51) | KDM4EALDH1A1HPGDMAOASMN1; SMN2 | |
| SCHEMBL19744020 | 0.78 | KDM4E (0.68) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL27785538 | 0.78 | KCNH2 (0.49) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL28291736 | 0.78 | CA1 (0.62) | KDM4EALDH1A1HPGDMAOASMN1; SMN2 | |
| SCHEMBL29782821 | 0.77 | GAA (0.55) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222183-A1 | BENZOPYRAN DERIVATIVES | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. (IT) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001029022-A1 | BENZOPYRAN DERIVATIVES | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) | 2001-04-26 | — | — | WO | disclosed |